Mesothelioma top Disease

Mesothelioma

Mesothelioma is a rare, aggressive form of cancer, which develops in the lungs, stomach or heart lining. Due to asbestos, there is no known cure for mesothelioma and there is very poor forecast in it.

According to a report by the Center Contains for Disease Control in 2017, 2,400 - 2,800 people diagnose mesothelioma every year in the United States. Those who have worked with asbestos or have contacted them are at high risk of developing mesothelioma, after exposure to asbestos, symptoms of mesothelioma may take 20 to 50 years.

Life expectancy is bad for mesothelioma patients because there is no cure for this disease. The condition of disease, cell type and tumor location are the most important factors for the patient's survival. The effects of overall health, age and cancer spreading factors also affect the patients.

What are mesothelioma cancer?

Mesothelioma begins in mesothelium cells, a group of cancerous (fatal) tumor cancer cells that can grow and destroy the tissue tissue. It may also spread in other parts of the body (metastasis).

Mesothelium is a membrane that covers and protects your internal organs. It is composed of 2 layers. The inner layer wraps around different organs including the lungs, heart and stomach. The outer layer creates a pouch around the internal layer, there is a small amount of fluid between the 2 layers, so that the organ can be easily transferred.

There are different names of mesothelium, depending on where in the body. Mesothelium which protects the lung and cures it is called lung, the inner layer covering the lungs is called the intestinal pulmonary form. The outer layer, which underlines the inside wall of the chest, is called pyramidal puffery.

The mesothelium that covers the abdominal organs and lines the walls of the abdomen and pelvis is called the peritoneum. The inner layer is called the visceral peritoneum. It covers and supports most of the internal abdominal organs. The outer layer is called the parietal peritoneum. It lines the walls of the abdomen and pelvis.

he mesothelium is made up of mesothelial cells. These cells sometimes change and no longer grow or behave normally. These changes may lead to non-cancerous (benign) tumours, such as fibrous tumour of the pleura and multicystic mesothelioma. But in some cases, changes to the mesothelial cells can cause malignant mesothelioma.

Mesothelioma is a very rare type of cancer. It usually starts in the pleura, which is called pleural mesothelioma. This type of cancer makes up 70% to 80% of all mesotheliomas. Cancer can also start in the peritoneum, which is called peritoneal mesothelioma. This type of cancer makes up about 25% of all mesotheliomas.

Rarer types of mesothelioma can also develop. This includes pericardial mesothelioma, which starts in the membrane that surrounds the heart. Another rare type is mesothelioma of the tunica vaginalis testis, which starts in the outer lining of the testicle.

Mesothelioma

Mesothelioma is a cancerous tumor of mesothelioma that can grow and destroy near the tissue. It can also spread in other parts of the body (metastasis). Mesothelium is a lining that covers the outer surface of most internal organs. It can be called a different name, depending on which part it is covering.

Paval mesothelioma

The lung begins in the mesothelioma membrane, which includes the lung, which is called the lung, is the most common type of mesothelioma, more men than women are diagnosing lung Mesothelioma.

Peritoneal mesothelioma

Peritoneal mesothelioma begins in peritoneum, which contains many organs in the stomach and several organs in the stomach. This is the second most common type of mesothelioma, men and women are affected equally from peritoneal mesothelioma.

Rare mesothelioma

The following cancerous tumors of mesothelium are very rare.

Pericardial Mesothelioma begins around the heart of the heart (Pericardium). The most common symptoms of pericardial mesothelioma are heart problems due to the formation of tumors or fluid around the heart. There is chest pain, chest pain, which becomes worse with deep breathing or cough, problems in breathing, and feeling anxious or restless. Another symptom is to cure, where the heart feels like it is fluttering, faster or racing, treatment may include surgery, radiation therapy or chemotherapy. Pericardial Mesothelioma is a very bad prediction (predicted outcome)

Mesocylymosis of the tunica vaginalis begins in the layer that involves the testicles (tunica vaginalin). The most common symptom is pain and inflammation of testis and is the surgery to remove testicles and ovaries and lymph nodes in the area. Radiation therapy can be offered after surgery. The role of chemotherapy in the treatment of mesothelioma of tunica vaginalis is not known as this disease is very rare.

Mesothelioma cell type

Mesothelioma can also be described by tumor cell makeup, as seen on the bottom of a microscope there are 3 main cell types of mesothelioma

Epithelioid is the most common mesothelioma cell type, more favorable than other cell types of this type of forecast.

Sacromatoid, also called fibers, is the second most common mesothelioma cell type. This type of cell expands more rapidly than epithelioid cells.

Mixed, or bilateral, there are both epithelioid and circotide areas within the tumor. Tumors with more epithelioid cells have better circomodite cells than tumors.

Benign mesothelioma

A non-cancerous or benign mesothelioma mesothelioma develops, which does not spread in other parts of the body (metastasis). Cordial mesothelioma tumors are usually threatening life. They are usually removed from surgery and usually do not return (recursive) are some kind of benign mesothelioma

Fungal fibroid tumors

This tumor can start in thin tissue covering the lung (intestine size). It may also start in the thin tissue that surrounds chest lines and lungs (parietal lungs). Fibrous fibroid tumors can cause many symptoms of malignant mesothelioma symptoms, such as shortness of breath.

These types of tumors may occur after surgery, in some cases, a local fibrous tumor of the lungs is actually cancerous.

Multicastic mesothelioma

Multicultural mesothelioma makes many benign cysts

Ulcer

A bag in the body that is usually full of liquid or semi-solid material. On the thin layer of the inner stomach, peritoneum is said to be called mesothelioma more commonly found in women, it can be called benign cystic mesothelioma.

Adenomide mesothelioma

Such benign mesothelioma can start mesothelium in reproductive organs. In women, it can start in fallopian tubes. In men, it may start in the epididymis ducts, which carry sperm cells out of the testicles.

Risk factors for mesothelioma

A risk factor is something that increases the risk of developing cancer. It could be a behaviour, substance or condition. Most cancers are the result of many risk factors. Exposure to asbestos is the most important risk factor for mesothelioma.

Mesothelioma affects men much more often than women. This is probably because men are more likely to be exposed to asbestos at work.

Mesothelioma develops 15–40 years after someone is exposed to asbestos. As a result, it is uncommon in people under the age of 50 and the incidence of mesothelioma increases with age.

Risk factors are generally listed in order from most to least important. But in most cases, it is impossible to rank them with absolute certainty. Research shows that there is no link between smoking and a higher risk for mesothelioma.

Known risk factors

There is convincing evidence that the following factors increase your risk for mesothelioma.

Asbestos

Asbestos is the name of a group of minerals that occur naturally. It can be separated into long, thin fibres that are very fine. When someone breathes in these fibres, they can make their way to the smallest airways of the lung and into the mesothelium. The fibres get into the pleura, where they can eventually cause pleural mesothelioma. If they are coughed up and then swallowed, asbestos fibres can also settle in the peritoneum. This is the most likely cause of peritoneal mesothelioma.

The link between asbestos and mesothelioma has been well known for many years. According to the International Agency for Research on Cancer (IARC) and the US National Toxicology Program, all forms of asbestos are known to cause cancer. Most people with mesothelioma have a history of asbestos exposure.

Occupational exposure to asbestos is the strongest and most common risk factor for mesothelioma. The risk is related to how much asbestos you were exposed to and how long the exposure lasted. People exposed at an early age, for a long period of time and to greater amounts of asbestos are more likely to develop mesothelioma.

Asbestos has been widely used in building materials and many industries. People who may come into contact with asbestos while working include:

workers in asbestos mines or mills

construction workers, carpenters and painters

shipyard workers

cement plant workers

insulation workers

electricians

plumbing and heating tradespeople

demolition workers

automotive industry workers, including brake and clutch repair workers

people who work in buildings where asbestos was present and was disturbed during renovations

People who live near an asbestos mine or mill are also exposed to asbestos or asbestos dust in the air. Family members may also be exposed to asbestos from fibres that are brought home on a worker’s clothing.

Occasionally, mesothelioma develops in people who have never been exposed to asbestos.

Erionite

Erionite is known to cause cancer in people, and it is linked to pleural and peritoneal mesothelioma. It is a naturally occurring mineral that belongs to a group of minerals called zeolites. Zeolites are chemically related to asbestos and erionite has asbestos-like fibres.

Erionite is common in the soil in parts of Turkey. Materials made with erionite are used in construction in these regions. As a result, there are high rates of mesothelioma in these areas due to exposure to erionite.

Ionizing radiation

People given radiation therapy to the chest or abdomen to treat lymphoma, breast, lung or other types of cancer have a higher risk for mesothelioma.

Thorium dioxide (Thorotrast) is a radioactive contrast medium

contrast medium

A substance used in some diagnostic procedures to help parts of the body show up better on x-rays or other imaging tests. that was once used for imaging tests. People who were given thorium dioxide have a higher risk of developing mesothelioma many years after being exposed to it. Because it was found to increase the risk of some cancers, thorium dioxide is no longer used.

BAP1 gene mutation

The BAP1 gene is also called the BRCA1 associated protein 1 gene. It is a type of gene that helps control cell growth and may limit the growth of cancer cells (called a tumour suppressor gene). A rare mutation in the BAP1 gene may increase the risk for mesothelioma and melanoma of the skin and eye. Healthcare professionals may refer to people who have the BAP1 gene mutation as having BAP1 cancer syndrome.

People who are exposed to asbestos and have the BAP1 gene mutation are at an even higher risk of developing mesothelioma.

Unknown risk factors

It isn’t known whether or not the following risk factors are linked with mesothelioma. It may be that researchers can’t show a definite link or that studies have had different results. More research is needed to see if these are risk factors for mesothelioma:

simian virus 40 (SV40)

carbon nanoparticles

References